Polynucleotides are biostimulating molecules derived from purified DNA fragments that help support skin repair, hydration, and collagen production. When combined with microneedling, the treatment can enhance the delivery of polynucleotides into the skin, promoting tissue regeneration and improving overall skin quality.
Microneedling creates controlled microchannels in the skin, stimulating the body's natural healing response. Applying polynucleotides during or immediately after microneedling allows these regenerative molecules to penetrate more effectively, helping to support fibroblast activity, improve skin elasticity, and boost hydration.
Potential benefits of combining polynucleotides with microneedling include:
- Improved skin texture and tone
- Enhanced hydration and skin radiance
- Reduction in fine lines and wrinkles
- Increased collagen and elastin production
- Improved appearance of acne scars and other superficial scars
- Support for skin repair and recovery
Most patients experience mild redness and sensitivity for 24–72 hours following treatment. A course of treatments is often recommended to achieve optimal results, with improvements continuing over several weeks as collagen remodeling occurs.
This combination treatment is suitable for many skin types and is commonly used for facial rejuvenation, scar management, and improving overall skin health. A professional consultation is recommended to determine whether the treatment is appropriate for an individual's skin concerns and goals.